Heckle and Jeckle-Terry Toons-1946

Here we see the very first comic book adventure of the popular but down the line controversial (for their violent antics) talking magpies.

For Whom the Drum Beats-Steve Ditko-1961

Another of the many striking examples of wonderful pre-Spidey Ditko splashes.

The Heap-Ernest Schroeder-1952

Ernie Schroeder did a little bit of everything, drawing here and there throughout the comics field but also in magazine illustration, advertising, and later becoming the chief sculptor at the Franklin Mint. 

Happy-Hy Rosen-1952

This guy always impresses me as kind of a combination of Archie and Jughead!

The Flame-1941

GCD question marks this as being Lou Fine but I am really just not seeing it. Maybe very, very early Fine but I'm pretty sure he was already doing sharper stuff than this by this time.  

The Little Rascals-David Gantz-1958

Dave Gantz had a particularly pleasing art style, something like a cross between Mike Sekowsky and Wally Wood. Here we see him on Alfalfa, Spanky, and Our Gang, who got new comics stories this late due to the revival of the old films on TV.

He Made Me Into a Robot-Bill Ely-1962

Although largely forgotten today, Bill Ely was a 25 year DC veteran already by the time this story appeared in '62. If he's remembered at all these days, it's for his long run on Rip Hunter, Time Master.